The Principal Investigator (PI), or study doctor, ultimately is responsible for all aspects of conducting a research study, including the supervision of all Sub-Investigators and research personnel to whom study responsibilities may be delegated. While Principal Investigators may delegate responsibilities as appropriate, the PI’s are responsible for personally conducting or supervising the conduct of the research and for protecting the rights, safety, and welfare of the subjects enrolled in the research. The PI must ensure that all research is conducted in an ethical manner and in accordance with all federal, state, institutional policies, local laws and regulations. All PI’s are qualified individuals that are available to provide study subjects with reasonable medical care for any medical problems that arise during participation in the research that are, or could be, related to the research. All PI’s are qualified by education, training and experience in the area in which research is being conducted. The principal investigators affiliated with Centex Research Inc. are extremely committed to their research patients, have wonderful bed-side manner and are proud to be able to contribute to the world of clinical research.